Gene information
Official symbol GRM2
Official full name glutamate metabotropic receptor 2
Gene type protein-coding gene
Chromosome3p21.2
Alias symbolGPRC1B; mGlu2; MGLUR2
Gene familyGlutamate metabotropic receptors
Resources
Entrez Gene 2912
HGNC HGNC:4594
Ensembl ENSG00000164082
Vega OTTHUMG00000156902
UCSC uc010hlv.4
GO terms: 38 records
GO Description Category LogP Number of genes Detail
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway GO Biological Processes -9.16710904 33 More
GO:0007268 chemical synaptic transmission GO Biological Processes -4.44678751 35 More
GO:0007610 behavior GO Biological Processes -18.1916656 76 More
GO:0030424 axon GO Cellular Components -6.14132550 54 More
GO:0030425 dendrite GO Cellular Components -4.55233052 48 More
GO:0030534 adult behavior GO Biological Processes -6.59104580 21 More
GO:0032890 regulation of organic acid transport GO Biological Processes -14.1608908 23 More
GO:0032940 secretion by cell GO Biological Processes -8.42144465 43 More
GO:0035094 response to nicotine GO Biological Processes -8.07167727 14 More
GO:0042220 response to cocaine GO Biological Processes -3.16841106 5 More
GO:0042734 presynaptic membrane GO Cellular Components -4.19875640 10 More
GO:0043086 negative regulation of catalytic activity GO Biological Processes -41.1437610 130 More
GO:0043269 regulation of ion transport GO Biological Processes -36.9814668 116 More
GO:0043279 response to alkaloid GO Biological Processes -4.89883771 15 More
GO:0044070 regulation of anion transport GO Biological Processes -12.6410846 24 More
GO:0045211 postsynaptic membrane GO Cellular Components -5.83105498 30 More
GO:0046903 secretion GO Biological Processes -18.5147167 70 More
GO:0050433 regulation of catecholamine secretion GO Biological Processes -6.37680507 13 More
GO:0050801 ion homeostasis GO Biological Processes -12.0812968 60 More
GO:0050804 modulation of chemical synaptic transmission GO Biological Processes -15.2260557 60 More
GO:0051046 regulation of secretion GO Biological Processes -54.0079540 130 More
GO:0051896 regulation of protein kinase B signaling GO Biological Processes -30.5149255 55 More
GO:0051952 regulation of amine transport GO Biological Processes -10.5179624 22 More
GO:0051955 regulation of amino acid transport GO Biological Processes -5.24816080 10 More
GO:0055081 anion homeostasis GO Biological Processes -3.50343693 8 More
GO:0097060 synaptic membrane GO Cellular Components -5.94418548 20 More
GO:0097447 dendritic tree GO Cellular Components -4.82959150 49 More
GO:0098793 presynapse GO Cellular Components -4.56552653 42 More
GO:0098916 anterograde trans-synaptic signaling GO Biological Processes -4.44678751 35 More
GO:0098936 intrinsic component of postsynaptic membrane GO Cellular Components -4.76116234 10 More
GO:0099055 integral component of postsynaptic membrane GO Cellular Components -4.91964814 10 More
GO:0099177 regulation of trans-synaptic signaling GO Biological Processes -15.1793607 60 More
GO:0099240 intrinsic component of synaptic membrane GO Cellular Components -5.23284212 12 More
GO:0099536 synaptic signaling GO Biological Processes -6.00976162 42 More
GO:0099537 trans-synaptic signaling GO Biological Processes -5.17038357 38 More
GO:0099699 integral component of synaptic membrane GO Cellular Components -4.78109966 11 More
GO:0140352 export from cell GO Biological Processes -8.94733589 48 More
GO:1903530 regulation of secretion by cell GO Biological Processes -45.6472055 114 More
KEGG pathways: 3 records
KEGG Description Category LogP Number of genes Detail
hsa04072 Phospholipase D signaling pathway KEGG Pathway -3.77257282 17 More
hsa04080 Neuroactive ligand-receptor interaction KEGG Pathway -22.6219922 65 More
hsa05030 Cocaine addiction KEGG Pathway -1.78827574 6 More
Drug-Gene interaction
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Related drugs: 7 records
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
Chr3:51713043 hypomethylation epigenomics ischemic cardiac events[prognosis (bad)] myocardial infarction Thunders M et al. Epigenetics. 2019
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